Experts release projected stats for Bills-49ers Thanksgiving weekend blockbuster; Brock Purdy’s injury status emerges as focal point

Ahead of the NFL’s Thanksgiving weekend Sunday Night Football blockbuster between Josh Allen’s Buffalo Bills and Brock Purdy’s San Francisco 49ers, data analysts released updated projected player stats this morning. Taking into account the latest updates on Purdy’s potential availability this Sunday, and with boosted Sunday Night Football parlay odds now available from Bet365 Sportsbook, bettors and fans can gain key insights into likely player performances.
On Tuesday, we reported on Buffalo’s sterling record following bye weeks under Head Coach Sean McDermott, which was quickly overshadowed by question marks surrounding whether the shoulder injury that kept Brock Purdy from suiting up against the Vikings in NFL Week 12 will also prevent him from playing in NFL Week 13.
On Wednesday, Purdy was listed as a limited practice participant on San Francisco’s injury report.
Crucially, Purdy did conduct some passing exercises in Wednesday’s practice. While it should be noted that the same was true last week, the enormous importance of Sunday’s matchup to the 49ers’ prospects of making the 2024 NFL postseason has led most experts and analysts to believe that Brock Purdy is more likely to play against the Bills on Thanksgiving weekend than he is to miss his second straight game.
In light of this update, Dimers’ analysts conducted 10,000 simulations of the Bills-49ers Sunday Night Football showdown, operating under the assumption that Purdy will start at quarterback. The results are below. We will release updated coverage and projected stats throughout the week if further updates emerge as to Purdy’s status.
Based on 10,000 simulations and the latest player updates, here are the projected player stats for the NFL Week 13 Sunday Night Football game between the San Francisco 49ers and Buffalo Bills:
Starting QB: Josh Allen
Rushing:
Receiving:
Starting QB: Brock Purdy
Rushing:
Receiving:
Bet365 Sportsbook has unveiled a boosted odds parlay for Sunday Night Football, offering +1600 odds (up from +1400) on the following outcomes:
This parlay stands out due to the absence of a Brock Purdy leg, making it a safer option for bettors concerned about Purdy’s uncertain health status. Should Purdy struggle or not play, McCaffrey and Kittle remain integral to the 49ers’ offensive plans, and Josh Allen’s dual-threat ability ensures consistent touchdown opportunities for the Bills.
For prop bettors, the boosted odds significantly enhance the potential payout, while the structure of this parlay mitigates risk stemming from the quarterback situation. This makes the Bet365 boosted parlay one of the most attractive NFL prop betting options for Sunday Night Football.
Stay tuned for further updates as Brock Purdy’s availability is clarified later in the week. Dimers’ analysts will release revised projections based on new information, and sportsbooks like Bet365, DraftKings, Caesars, BetMGM, and FanDuel are all likely to update their odds.